GHRP-2 vs GHRP-6 vs Ipamorelin–Benefits, Results & Side Effects

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GHRP-2, GHRP-6, and Ipamorelin.

Individuals researching ways to increase HGH levels are likely to come across information about these growth hormone releasing peptides.

Despite the fact that these three peptides all stimulate the body to produce its own HGH, there are many differences between them.

This article will serve as a comparison between these three peptides. Should you stack them together? Should they stand alone? Or should you combine with other products?

GHRP-2 VS GHRP-6 VS Ipamorelin

Before diving into how to take these peptides, the results and side effects of GHRP-2, GHRP-6 and Ipamorelin, it is useful to first have a brief understanding of each:

GHRP-2: Also known as Growth Hormone Releasing Peptide 2, this compound stimulates the body to release HGH.

GHRP-2 belongs in the hexapeptide class, and this peptide hormone is generally considered easier to take than GHRP-6. Also, GHRP-2 is frequently implemented in long-term Hormone Replacement Therapy.

GHRP-6: Similar to GHRP-2, this peptide hormone boosts the quantity of natural growth hormone produced within the body but is a bit harder to take.

Ipamorelin: Ipamorelin is also a growth hormone peptide and is characterized by a slower, more steady release of growth hormone.

As such, the effects of Ipamorelin are some of the longest lasting when compared to other growth hormone releasing peptides. Many athletes and bodybuilders prefer this release schedule as it is more similar to how the body naturally releases GH.

Results for Bodybuilding

By increasing levels of growth hormone within the body, an individual can experience improved metabolism; improved metabolism leads to more efficient fat burning and improved recovery.

It’s no wonder why users are eager to explore the effects of these peptide hormones on their body building progress.

Recovery stage: All three of these peptide hormones improve the recovery stage, and that is directly due to the natural increase in growth hormone. As GH increases, the body is able to both protect existing muscle and build new muscle tissue.

Cutting stage: Of these three, GHRP-6 can best improve the cutting phase of an athlete, but many athletes struggle with the intense hunger associated with using GHRP-6.

Overall results: Bodybuilders will more than likely see progress in the gains, fat loss during cutting, and better recoveries, but it’s best to keep expectations realistic.

These peptide hormones are designed for hormone replacement therapy and while users will experience growth, it will not mimic the growth of a HGH routine. This is especially true of GHRP-2.

GHRP-6: While GHRP-6 does successfully facilitate the release of GH, the results are not the same as if HGH was taken. With that in mind, GHRP-6 leads to more impressive bodybuilding results when combined with another growth hormone releasing peptide.

Ipamorelin: For bodybuilding purposes, Ipamorlein is one of the easiest-on-the-body secretagogues available. With its slow release that mimics the body’s release schedule, the stable levels lead to a more desirable recovery.


Part of exploring the pros and cons of each peptide hormone is learning about the dosage instructions.

GHRP-2: Because GHRP-2 is often used in long term hormone replacement therapies, it’s not uncommon to find individuals using this indefinitely.

However, dosing definitely ranges depending on intended use (100-300mcg). Two injections per day are sufficient, although these injections should be done on an empty stomach.

GHRP-6: Like GHRP-2, the daily dose can vary quite a bit from 50-500mcg. However, if this is combined with another GHRP, then the range is reduced to 50-150mcg.

While two doses of GHRP-2 is sufficient, doses of GHRP-6 can be bumped up to 3 per day. Additionally, this hormone works best when taken on an empty stomach.

Ipamorelin: Bodybuilders who opt for Ipamorelin use it for at least 8 weeks, although 12 weeks is the ideal period of use.

Doses range from 200-300mcg and should be injected 2-3x per day. Because Ipamorelin needs to be administered multiple times each day, many users prefer to inject subcutaneously.

Legal Status

Neither GHRP-2, GHRP-6, nor Ipamorelin are legal for bodybuilding purposes.

However, all three of these are available for purchase online from research companies.

Ipamorelin in particular can be purchased by researchers but it cannot be legally purchased for personal human use.

On the other hand, GHRP-2 can be legally used by humans as part of a long term hormone replacement therapy.

Side Effects

Reviewing side effects of any medication is always a good practice and that is no different for the human growth release peptides. As with any injectable, a common side affect includes pain and tenderness at the injection site.

GHRP 2: This GHRP is one of the most user friendly available, which the most common side effect pain at the injection site. However, when GHRP-2 is taken in high doses, prolactin-induced gynecomastia has been recorded.

GHRP-6: Users comment frequently that use of this peptide leads to an increase in hunger. In addition, the drop in blood sugar can lead to headaches.

Ipamorelin: There are no reported estrogenic or androgenic side effects. In addition to injection site pain, users may experience headaches, but a few dietary changes can alleviate that.



The price of these GHRP vary quite a bit as they are sourced differently. Because GHRP-2 can be dispensed legally with a prescription, price will vary according to the pharmacy chosen and any insurance coverage.

On the other hand, Ipamorelin and GHRP-6 are only available online through companies specializing in research chemicals. Ipamorelin runs about $15-25 for 2mg while GHRP-6 can run up to $35 for 2mg.

At the end of the day, GHRP-2, GHRP-6, and Ipamorelin boost the body’s production of GH without “massive gains” or unmanageable side effects.

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