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One of the most notorious and misunderstood of Primobolan side effects is its effect on hair.
What is the truth about Primobolan and hair loss?
Is it a risk for everyone, or is such a side effect limited to those with a hereditary or genetic predisposition to male pattern baldness?
Primobolan, as an anabolic androgenic steroid, has the potential to cause a number of adverse reactions and unexpected issues.
Primobolan side effects range from mild and temporary to more severe, and some can potentially be long-term or even life-threatening.
Primobolan Side Effects – Hair Loss?
Primobolan side effects may include:
Natural testosterone suppression
Suppression of good HDL cholesterol
Increased bad LDL cholesterol
Virilization in women
Possible body hair growth and acne
Effects on the heart usually don’t include high blood pressure, but could
There are others but the big question when it comes this steroid is… Primobolan and hair loss; are they connected?
Primobolan (Methenolone acetate) is a steroid that is derived from dihydrotestosterone or DHT.
DHT is a metabolite of testosterone. DHT is reputed to be five times stronger than testosterone.
This conversion from testosterone into dihydrotestosterone is achieved through enzyme (Type II 5-alpha-reductase) functions and activities.
The higher the levels of 5-alpha reductase, the higher the levels of testosterone converted into the dihydrotestosterone, the metabolite, in the body.
Do increased levels of DHT contribute to increased hair loss?
Primobolan Depot Hair Loss
Is Primobolan and hair loss fact or fiction?
Some articles found on bodybuilding websites and muscle building forum board discussion threads claim that hair loss is not a given, but that it depends on genetic predisposition.
In fact, “Primobolan and hair loss” is one of the more common search terms associated with use of the synthetic anabolic androgenic steroid.
The general consensus is that unless a man has a propensity or genetic family history of male pattern baldness, it’s likely to be one of the steroids that don’t cause hair loss.
Androgens like DHT and testosterone do contribute to facial hair, pubic, and otherwise normal body hair growth in men, and DHT does contribute to its growth.
And it is true that male pattern baldness is often inherited.
Dihydrotestosterone is required for most hair growth. Nevertheless, it can be damaging to growth of hair on the head. Why?
The ability of dihydrotestosterone to bind to hair follicle androgen receptors, triggering them to shrink. This can result in hair loss.
In order to reduce the risk of triggering hair loss, bodybuilders often use prescription strength hair loss medications and incorporate them into their stacks.
Finasteride (brand name Propecia or Proscar) is one of the most common, but results can be mixed. Products like finasteride are not a fix-all when it comes to Primobolan and hair loss.
N2 Shampoo can be bought on Amazon, and may also be helpful.
Just because it’s a milder steroid doesn’t make it one of the safest steroids for hair loss, because the Androgenic side effects will still kick in. The following steroids cause hair loss:
Whereas the best steroids for hair loss include (as in they’re less likely to cause hair loss, but still may):
Will hair loss from steroids grow back? Unfortunately no. Steroids do not cause hair loss, they simply speed up the process for those predisposed to it genetically.
What Does Primobolan Do?
Primobolan is considered by many bodybuilders and athletes to be relatively mild, thus having milder side effects.
Known by its chemical name, methenolone acetate, it’s not generally considered a strong steroid that triggers many negative side effects.
Primobolan is found in both oral and injectable solutions, depending on manufacturer, country of origin, or underground lab.
The Primobolan injectable version is known as Primobolan Depot.
Depending on the source, it can come in a variety of milligram strengths, and depending on skills of the manufacturers and chemical composition.
Slightly different chemical compositions are also related to their molecular structure depending on the ester attached to it.
Esters modify drugs to regulate their absorption rate in the body as well as half-life. For example:
Methenolone acetate: C22H32O3 (oral form)
Methenolone enanthate: C27H42O3 (injectable form)
Acetate provides a faster surge of Primobolan into the bloodstream, but it has a shorter half-life. Conversely, enanthate has a slower dispersion rate but has a longer half-life.
Primobolan, as an oral anabolic androgenic steroid is considered to be milder or gentler forms of anabolic steroids found on the market today.
Nevertheless, Primobolan side effects are noted among users, and these effects are not just related to milligram strength or frequency of use.
Primobolan is a synthetic or laboratory developed anabolic androgenic steroid that mimics the effects of testosterone in the body.
The potency or strength of Primobolan and is reputed to be a bit less than body-produced (endogenous) testosterone.
Bodybuilders often turn to Primobolan because of its lower potential to produce negative and undesired estrogenic and progestational activity in the body.
Primobolan Side Effects on the Heart
Primobolan is known to pose some side effects to the cardiovascular system, such as causing negative cholesterol changes. This is common with all anabolic steroids.
Methenolone can cause the reduction of HDL and the increase in LDL (bad cholesterol).
This can raise one’s chances of getting arteriosclerosis, and the problem may be elevated with higher dosages.
Other factors that may increase the negative cholesterol alteration include the route of administration and duration of use.
When it comes to the method of administration, oral ingestion is known to be the worst for causing negative impacts to cholesterol compared to injectable anabolic steroids.
This is because the human liver is responsible for processing cholesterol, and an increase in hepatotoxicity due to oral anabolic steroid administration may exacerbate negative cholesterol changes.
Performance users recommend a clean diet that includes healthy cholesterol promoting foods such as omega 3 fatty acids and fish oils every day during a cycle of Methenolone This is one way bodybuilders seek to counteract this Primobolan side effect and keep good and bad cholesterol in check.
Primobolan Side Effects on the Liver
Both oral Primobolan (Methenolone Acetate) and Injectable Primobolan (Methenolone Enanthate) are both understood to be without the liver toxicity associated with C17-alpha alkylated anabolic steroids.
Primobolan is believed to have no measurable hepatotoxic effects on the body, even when orally administered.
Primobolan has not been observed to cause changes in liver enzymes that would raise concern, and it is not known to resist hepatic breakdown.
Only one incident of death due to hepatotoxicity and liver failure from oral Primobolan has been reported in an elderly male patient who had been given the prescription to help treat anemia.
Oral Primobolan does have a certain amount of resistance to breakdown and metabolism in the liver, and this may increase the risk of liver problems at higher dosages.
Injectable Primobolan (Methenolone Enanthate) is believed to be completely free of risk to the liver.
Primobolan Side Effects on the HPTA
In the event that one uses anabolic steroids for performance and physique enhancement, it can cause suppression if not the complete shutdown of the natural production of testosterone.
This happens because steroids can adversely influence the Hypothalamic Pituitary Testicular Axis (HPTA) and its negative feedback loop.
As much as it is flaunted as an anabolic steroid that’s gentle and mild, Primobolan is no exception to this.
The idea that Methenolone does not cause testosterone suppression is a false rumor. 1970 clinical data has shown that administering prescribed doses at 30-45mg per day can suppress the HPTA as much as 15-65%.
Physique and performance enhancement dosages are typically much higher than those used in these studies. Most bodybuilders tend to start at 100mg of Primobolan every single day.
Even if it is true that the suppression of Primobolan is normally lower in contrast with other anabolic steroids, low testosterone during and following a cycle of this drug is a real threat.
Most physique builders who use steroids engage in a structured Post Cycle Therapy (PCT) program. During PCT, users will use hormone balancing compounds like HCG and Nolvadex for a period of 4-6 weeks immediately after the culmination of any cycle to restore the body’s natural production of testosterone.
Individual who do not undergo the PCT program properly are viewed to be at a greater risk of permanent damage to their HPTA. At this point, medical intervention may then be necessary.
Benefits VS Primobolan Side Effects
Primobolan provides a number of benefits for men and women, including:
Anabolic or tissue building potential (mild)
Ability to preserve lean muscle mass
Enhance production of red blood cells
Improve protein synthesis
Resists aromatization or conversion from testosterone into estrogen
Beginners should always use caution when introducing a new anabolic androgenic steroid into their routines. Start at lower than recommended dosages to see how the body initially reacts to it.
Primobolan Side Effects in Women
In spite of its “gentler” reputation, Primobolan should be used with caution by women.
As an anabolic androgenic steroid, it does have the potential to trigger virilism or development of male characteristics due to its androgenic nature.
Primobolan side effects should not be ignored, nor the potential for Primobolan and hair loss potential.
Every person may react differently depending on milligram strength, frequency of dosage, and length of use.